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Nucleic Acids Symposium Series 2001 1(1):193-194; doi:10.1093/nass/1.1.193
© 2001 by Oxford University Press
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Regulation of aggregated structure of dye molecules by DNA hybridization

Hiroyuki Asanuma, Kenji Shirasuka, Tohru Takarada and Makoto Komiyama

Research Center for Advanced Science and Technology, The Univ. of Tokyo, Komaba, Meguro-ku, Tokyo 153-8904, Japan

Dye H-aggregates were successfully created by introducing multiple Methyl Red molecules consecutively in the single stranded DNA. By the presence of its complementary DNA, however, the H-band disappeared and new peak appeared at longer wavelength, indicating that aggregated structure changed by the duplex formation. Thus, supramolecular structure of the dye aggregates was successfully controlled by use of DNA.


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