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Nucleic Acids Symposium Series 2007 51(1):235-236; doi:10.1093/nass/nrm118
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© 2007 Oxford University Press

Parallel processable light-driven DNA logic gate

Shinzi Ogasawara1, Takehiro Ammi2 and Kenzo Fujimoto2,*

1Bioengineering Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan and
2School of Materials Science, Japan Advanced Institute of Science and Technology, 1-1 Asahidai, Nomi, Ishikawa 923-1292, Japan

*Corresponding Author. kenzo{at}jaist.ac.jp

Abstract

Here, we report the construction of a photochemical DNA logic circuit made entirely of DNA and implemented with sequence-specific photo-cleavage (SSPC) of photocrosslinking sites enclosed in the gate strand. As example, we demonstrate the performance of logic operations including NOT, AND, OR, and full-adder using a SSPC reaction.


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