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Nucleic Acids Symposium Series 2007 51(1):37-38; doi:10.1093/nass/nrm019
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© 2007 Oxford University Press

Construction of supramolecular assemblies and self-organized structures using oligo-DNAs

Yuichi Ohya1,2,*, Takayuki Nishi1, Tomoyoshi Nohori1, Souya Jo1, Koji Ohta1, Kenta Jozuka1 and Tatsuro Ouchi1,2

1Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering &
2High Technology Research Center, Kansai University, 3-3-35 Yamate, Suita, Osaka 564-8680, Japan

*Corresponding Author. E-mail: yohya{at}ipcku.kansai-u.ac.jp

Abstract

To obtain fundamental theories for construction of self-organized structures using oligonucleotides, we constructed multiple aggregates with half-sliding oligo-DNAs. We used several types of half-sliding oligo-DNAs with different stability and number of residues. The formation of multiple aggregates by the oligo-DNAs was confirmed by size exclusion chromatography (SEC). The shape of the aggregates was investigated by atomic force microscope (AFM), and linear structures of multiple aggregates of half-sliding oligo-DNAs were observed.


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