Skip Navigation

Nucleic Acids Symposium Series 2008 52(1):155-156; doi:10.1093/nass/nrn079
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Bordeau, G.
Right arrow Articles by Teulade-Fichou, M.-P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bordeau, G.
Right arrow Articles by Teulade-Fichou, M.-P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2008 Oxford University Press

This article appears in the following Nucleic Acid Symposium Series issue: Joint Symposium of the 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and the 35th International Symposium on Nucleic Acids Chemistry [View the issue table of contents]

New triarylamine-based far-red DNA stainers with high two-photon absorption properties

G. Bordeau1, E. Faurel1, C. Allain1, R. Lartia1, F. Schmidt1, C. Fiorini-Debuisschert2, F. Charra2, G. Metge2, P. Tauc3 and M.-P. Teulade-Fichou1,*

1Institut Curie, CNRS UMR-176, centre universitaire, 91405 Orsay France 2CEA Saclay, DSM/DRECAM/SPCSI, 91191 Gif-sur-Yvette, France 3LBPA- Institut d’Alembert, 94230 Cachan, France.

*Corresponding Author. E-mail: mp.teuladefichou{at}curie.u-psud.fr

Abstract

A series of red emitting vinyl-triphenyamines (TP) have been synthesized and evaluated for their two photon absorption (2PA) properties. These compounds are virtually non fluorescent in the free state but exhibit a bright red fluorescence upon binding to doublestranded DNA, both in one- and two-photon absorption. This feature allows one- and two-photon confocal imaging in cells of nuclear DNA with an excellent contrast. Derivatizable analogues for covalent bioconjugation to oligonucleotides are described and variation on the structure is discussed.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.