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Nucleic Acids Symposium Series 2008 52(1):683-684; doi:10.1093/nass/nrn345
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© 2008 Oxford University Press

This article appears in the following Nucleic Acid Symposium Series issue: Joint Symposium of the 18th International Roundtable on Nucleosides, Nucleotides and Nucleic Acids and the 35th International Symposium on Nucleic Acids Chemistry [View the issue table of contents]

Addressable Molecular Node Assembly – High Information Density DNA Nanostructures

Erik Lundberg1,*, John Tumpane1, Ravindra Kumar2, Peter Sandin1, Nittaya Gale2, Iris S. Nandhakumar2, Bo Albinsson1, Per Lincoln1, L. Marcus Wilhelmsson1, Tom Brown2 and Bengt Nordén1

1Department of Chemical & Biological Engineering/Physical Chemistry, Chalmers University of Technology, Kemivägen 10, SE-412 96, Gothenburg, Sweden
2School of Chemistry, University of Southampton, Highfield, S017 1BJ, Southampton, UK

*Corresponding Author. E-mail: erik.p.lundberg{at}chalmers.se

Abstract

The inherent self-assembly properties of DNA make it ideal in nanotechnology. We present a fully addressable DNA nanostructure with the smallest possible unit cell, a hexagon with a side-length of only 3.4 nm.2,3 Using novel three-way oligonucleotides, where each side has a unique double-stranded DNA sequence that can be assigned a specific address, we will build a non-repetitive two-dimensional grid.


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