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Nucleic Acids Symposium Series 2001 1(1):1-2; doi:10.1093/nass/1.1.1
© 2001 by Oxford University Press
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Poly(oligonucleotide)conjugates: Applications in assembling nanoparticles and in detecting DNA sequences

Robert L. Letsinger, Chad A. Mirkin, So-Jung Park, Garimella Viswanadham and Ligang Zhang

Department of Chemistry, Northwestern University, Evanston, IL 60208, USA

The chemistry of oligonucleotide-nanoparticle conjugates is described. Examples are provided to illustrate (i) the utility of oligonucleotide linkers in constructing ordered nanoparticle assemblies and (ii) applications of nanoparticles as reporters for nucleic acid hybridization.


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