© 2003 by Oxford University Press
Synthetic study of cytosaminomycins using the intramolecular glycosylation as a key step
Faculty of Education, Yokohama National University, Tokiwadai 79-2, Hodogaya-ku, Yokohama 240-8501, Japan
2',6'-Dideoxy-ß-D-hexopyranosyl pyrimidine nucleoside, which is a component of anticoccidal antibiotics cytosaminomycins, was synthesized in a stereoselective manner via the intramolecular pyrimidine delivery method. Further glycosylaion of the 4'-position with a glycosyl fluoride gave the disaccharide nucleoside skeleton of the cytosaminomycins.