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Nucleic Acids Symposium Series 2005 49(1):15-16; doi:10.1093/nass/49.1.15
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© 2005 Oxford University Press

Nucleosides as anticancer agents: from concept to the clinic

John A. Secrist, III

Southern Research Institute, Birmingham, AL USA

The continuing use of nucleosides as anticancer agents is discussed. Examples include the newly approved drug clofarabine as well as 4'-thio-ara-C, a drug that has initiated clinical trials. New directions in anticancer drug discovery will also be discussed.


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