Skip Navigation

Nucleic Acids Symposium Series 2006 50(1):297-298; doi:10.1093/nass/nrl148
This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Nonogawa, M.
Right arrow Articles by Makino, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nonogawa, M.
Right arrow Articles by Makino, K.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2006 Oxford University Press

Chemical natures and application of 6-formylpterin derivatives

Mitsuru Nonogawa1, Sommani Piyanart1, Toshiyuki Arai2, Nobuyuki Endo3, Seung Pil Pack4,5, Tsutomu Kodaki1,5 and Keisuke Makino4,5

1 Institute of advanced Energy, Kyoto University, Uji 611-0011, Japan, 2 Department of Anesthesia, Kyoto University Hospital, Kyoto 606-8507, Japan, 3 Department of Research and Development, The Wakasa Wan Energy Research Center, Tsuruga 914-0129, Japan, 4 International Innovation Center, Kyoto University, Kyoto 606-8501, Japan, 5 CREST, Japan Science and Technology Agency

Pterin, an analog of guanine, is an electron transfer compound in biological systems. Among the analogs, 6-formylpterin (6FP) has been demonstrated to have many marked physiological and pharmacological activities. In vitro, 6FP converts molecular oxygen to reactive oxygen species (ROS) in the presence of NADH or NADPH under light illumination, with the oxidation of NADH is to NAD+. In the present study, it has been elucidated that some of 6FP derivatives in which the 3-position of 6FP is modified have such unique activities even in the dark where the most of in vivo biological events occur.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.